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Article

Genetics of systemic sclerosis

28 Aug 2015

Abstract excerpt

PURPOSE OF REVIEW: Large-scale and follow-up genetic association studies in systemic sclerosis (SSc) have implicated over 40 regions in disease risk, 15 of which with robust associations. Nevertheless, the causal variants and the functional mechanisms underlying the genetic associations remain elusive, and the reasons for the higher disease burden in African Americans unknown. Incorporating tools from diverse...

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PMID: 26317679
DOI: 10.1097/bor.0000000000000214

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