Article

Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1 syndrome

2021-07-05

Abstract excerpt

There is increasing evidence that mitochondrial homeostasis - influenced by both genetic and environmental factors - is crucial in neurodevelopment. FOXP1 syndrome is a neurodevelopmental disorder that manifests motor dysfunction, intellectual disability, autism and language impairment. In this study, we used a Foxp1 +/− mouse model to address whether cognitive and motor deficits in FOXP1 syndrome are associated...

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Literature Corpus work: 02bf674c-1804-5a22-8c84-d9527dddfadf
DOI: 10.1101/2021.07.05.451143

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