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Article

Prospective investigation of FOXP1 syndrome.

Molecular autism - 1 Jan 2017

Siper Paige M, De Rubeis Silvia, Trelles Maria Del Pilar, Durkin Allison, Di Marino Daniele, Muratet François, Frank Yitzchak, Lozano Reymundo, Eichler Evan E, Kelly Morgan, Beighley Jennifer, Gerdts Jennifer, Wallace Arianne S, Mefford Heather C, Bernier Raphael A, Kolevzon Alexander, Buxbaum Joseph D

Abstract excerpt

BACKGROUND: Haploinsufficiency of the forkhead-box protein P1 (FOXP1) gene leads to a neurodevelopmental disorder termed FOXP1 syndrome. Previous studies in individuals carrying FOXP1 mutations and deletions have described the presence of autism spectrum disorder (ASD) traits, intellectual disability, language impairment, and psychiatric features. The goal of the present study was to comprehensively characterize...

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Topics

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Share to Mutation, Missense
Share to Protein Structure, Tertiary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Repressor Proteins

Share to Autism Spectrum Disorder

Share to Developmental Disabilities

Share to Forkhead Transcription Factors

Share to Intellectual Disability

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Source

Open in PubMed Open full text

Identifiers

PMID: 29090079
DOI: 10.1186/s13229-017-0172-6
PMCID: PMC5655854

Genes

FOXP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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