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Article

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

Genes & development - 15 Oct 2015

Araujo Daniel J, Anderson Ashley G, Berto Stefano, Runnels Wesley, Harper Matthew, Ammanuel Simon, Rieger Michael A, Huang Hung-Chung, Rajkovich Kacey, Loerwald Kristofer W, Dekker Joseph D, Tucker Haley O, Dougherty Joseph D, Gibson Jay R, Konopka Genevieve

Abstract excerpt

Mutations in the transcription factor Forkhead box p1 (FOXP1) are causative for neurodevelopmental disorders such as autism. However, the function of FOXP1 within the brain remains largely uncharacterized. Here, we identify the gene expression program regulated by FoxP1 in both human neural cells and patient-relevant heterozygous Foxp1 mouse brains. We demonstrate a role for FoxP1 in the transcriptional...

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Source

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Identifiers

PMID: 26494785
DOI: 10.1101/gad.267989.115
PMCID: PMC4617974

Genes

FOXP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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