Article
Metabolic zonation and characterization of tissue slices with spatial transcriptomics
2025-11-12
Abstract excerpt
The exchanges of small molecules between cells and their environments are essential for the formation of functioning tissues. To study them at scale, we developed Harreman (Basque for “receive and give”), an algorithm for identifying metabolic crosstalk from spatially resolved transcriptomics of intact tissues. Unlike previous methods, which primarily focus on the secretion or reception of protein signals, Harrema...
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Identifiers and source
- Literature Corpus work
- 02b82da0-6970-58a8-a8fb-a1e121f23362
- DOI
- 10.1101/2025.11.11.687271