Article

Metabolic Reallocation in the Tumor Microenvironment of Colorectal Cancer at Single-cell Resolution

2025-04-11

Abstract excerpt

<title>Abstract</title> <p>Metabolic reprogramming of diverse cell types within the tumor microenvironment (TME) is crucial for tumor progression. While previous single-cell studies have identified a set of up- or down-regulated pathways, they often overlook the broader question of how metabolic activity is dynamically allocated among competing processes. Here we present a computational framework integrating mult...

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Literature Corpus work: 13b52877-cbd7-5517-8ace-7b81c1177397
DOI: 10.21203/rs.3.rs-5978633/v1

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