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SHINE: Decoding transcriptional-metabolic microenvironments through higher-order spatial integration

2026-07-16

Abstract excerpt

Spatial omics technologies are expanding to co-profile transcriptomics and metabolomics on the same tissue slide, providing complementary views of gene expression and biochemical activity to reveal molecular programs within native tissue microenvironments. However, integrating the transcriptome and metabolome remains technically challenging due to spatial misalignment, resolution disparity, and higher-order cross-...

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Literature Corpus work
62358902-5a2d-563b-aad8-47dd885ae0da
DOI
10.64898/2026.07.10.737648
Open publication

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