Article

MEBOCOST: Metabolite-mediated Cell Communication Modeling by Single Cell Transcriptome

2022-10-07

Abstract excerpt

<title>Abstract</title> <p>We developed MEBOCOST, an algorithm for quantitatively inferring metabolite-mediated intercellular communications using single-cell RNA-seq data. The algorithm identifies cell-cell communications in which metabolites, such as lipids, are secreted by sender cells and traveled to interact with sensor proteins of receiver cells. The sensors on the receiver cell include the cell surface rec...

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Literature Corpus work: 881817a6-1ccc-57ab-b1c1-2e28007bb97b
DOI: 10.21203/rs.3.rs-2092898/v1

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