Article

Genetically informed single-cell and spatial mapping of metabolic programs in human health and disease

2026-06-29

Abstract excerpt

Defining cell-type-specific endogenous metabolic features, the spatial distribution of cell-level metabolic states and cellular responses to exogenous metabolites is very important for understanding disease mechanisms. However, existing transcriptome-based metabolic models primarily infer intracellular reaction or pathway-level activities, and therefore cannot directly assess associations between individual metabo...

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Identifiers and source

Literature Corpus work: 278e7a2f-c445-5df2-88ef-9ba2aea41236
DOI: 10.64898/2026.06.25.734643

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