Article

MEBOCOST: Metabolite-mediated Cell Communication Modeling by Single Cell Transcriptome

2022-05-31

Abstract excerpt

We developed MEBOCOST, a computational algorithm for quantitatively inferring metabolite-mediated intercellular communications using single cell RNA-seq data. The algorithm identifies cell-cell communications in which metabolites, such as lipids, are secreted by sender cells and traveled to interact with sensor proteins of receiver cells. The sensor proteins on receiver cell might be cell surface receptors, transp...

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Literature Corpus work: 20d57e28-90b7-53bd-8914-16b1c61ed353
DOI: 10.1101/2022.05.30.494067

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