Article

An Integrated Pipeline for Cell-Type Annotation, Metabolic Profiling, and Spatial Communication Analysis in the Liver using Spatial Transcriptomics

2026-02-10

Abstract excerpt

The liver acts as a central metabolic hub, integrating systemic signals through a spatially organized pattern known as zonation, driven by the coordinated activity of diverse cell types including hepatocytes, stellate cells, Kupffer cells, endothelial cells, and immune populations. Spatial transcriptomics (ST) enables the profiling of thousands of cells with spatial resolution in a single experiment, facilitating...

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Literature Corpus work: 57bbbb10-be90-5176-ab24-af3dabe7e2a4
DOI: 10.64898/2026.02.07.704573

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