Article

Atypical depression is associated with a distinct clinical, neurobiological, treatment response and polygenic risk profile

2025-08-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Atypical depression is considered a distinct clinical subtype of major depression, yet its predictive validity and clinical utility remain contested. We investigated association between atypical depression and clinical characteristics, genetic profiles, and antidepressant responses. <h4>Methods</h4> Among 14,897 participants from the Australian Genetics of Depression Study...

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Literature Corpus work: 597d1b88-4f57-545d-9793-62ce521bcf49
DOI: 10.1101/2025.08.05.25333073

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