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Article

Depression with atypical neurovegetative symptoms shares genetic predisposition with immuno-metabolic traits and alcohol consumption.

Psychological medicine - 1 Mar 2022

Badini Isabella, Coleman Jonathan R I, Hagenaars Saskia P, Hotopf Matthew, Breen Gerome, Lewis Cathryn M, Fabbri Chiara

Abstract excerpt

BACKGROUND: Depression is a highly prevalent and heterogeneous disorder. This study aims to determine whether depression with atypical features shows different heritability and different degree of overlap with polygenic risk for psychiatric and immuno-metabolic traits than other depression subgroups. METHODS: Data included 30 069 European ancestry individuals from the UK Biobank who met criteria for lifetime...

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Identifiers

PMID: 32624019
DOI: 10.1017/S0033291720002342
PMCID: PMC8961332

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