Neuroimaging Methods to Map In Vivo Changes of OXPHOS and Oxidative Stress in Neurodegenerative Disorders

Abstract excerpt

Mitochondrial dysfunction is a pathophysiological hallmark of most neurodegenerative diseases. Several clinical trials targeting mitochondrial dysfunction have been performed with conflicting results. Reliable biomarkers of mitochondrial dysfunction in vivo are thus needed to optimize future clinical trial designs. This narrative review highlights various neuroimaging methods to probe mitochondrial dysfunction....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced MRI Techniques and Applications
• Share to Metabolism and Genetic Disorders
• Share to Mitochondrial Function and Pathology