Article
Mitochondrial Dysfunction in Alzheimer’s Disease: A Biomarker of the Future?
11 Jan 2021
Abstract excerpt
Alzheimer's disease (AD) is the most common cause of dementia worldwide and is characterised pathologically by the accumulation of amyloid beta and tau protein aggregates. Currently, there are no approved disease modifying therapies for clearance of either of these proteins from the brain of people with AD. As well as abnormalities in protein aggregation, other pathological changes are seen in this condition. The...
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