Article
Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Aug 2015
Regele Florina, Jelencsics Kira, Shiffman Dov, Paré Guillaume, McQueen Matthew J, Mann Johannes F E, Oberbauer Rainer
Abstract excerpt
Chronic kidney disease (CKD) affects 10-13% of the general population and diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD). In addition to known demographic, biochemical and lifestyle risk factors, genetics is also contributing to CKD risk. In recent years, genome-wide association studies (GWAS) have provided a hypothesis-free approach to identify common genetic variants that could...
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