Article

<i>In vitro</i> comparison of Aβ-targeting SNIPR, synNotch, and TRUCK for cell-based drug delivery in Alzheimer’s disease

2026-05-04

Abstract excerpt

Pioneering research is adapting chimeric antigen receptors (CARs) from oncology to Alzheimer’s disease (AD) by targeting amyloid beta (Aβ). Newer synthetic receptor systems can go beyond, transforming cells into targeted biological drug factories that can couple Aβ detection to synthesis and secretion of genetically encoded therapeutics. Among candidate systems, T cells Redirected for Universal Cytokine Killing (T...

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Literature Corpus work: 008805d4-d86e-5ae3-b708-5a39e7ea95d2
DOI: 10.64898/2026.04.29.721717

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