Article

Improved Deep Learning Prediction of TCR-HLA Associations

2024-11-25

Abstract excerpt

Understanding the relationship between T cell receptors (TCRs) and human leukocyte antigens (HLAs) is essential for elucidating immune response specificity, uncovering mechanisms of autoimmunity, and advancing targeted immunotherapies. We have previously developed a deep learning method, DePTH (Deep Learning Prediction of TCR-HLA associations), to predict the association between a TCR and an HLA based on their ami...

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Literature Corpus work: 0076cf87-243d-5eb5-b817-221e1951b93d
DOI: 10.1101/2024.11.22.624910

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