Article

NetTCR: sequence-based prediction of TCR binding to peptide-MHC complexes using convolutional neural networks

2018-10-03

Abstract excerpt

Predicting epitopes recognized by cytotoxic T cells has been a long standing challenge within the field of immuno- and bioinformatics. While reliable predictions of peptide binding are available for most Major Histocompatibility Complex class I (MHCI) alleles, prediction models of T cell receptor (TCR) interactions with MHC class I-peptide complexes remain poor due to the limited amount of available training data....

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Literature Corpus work: 4ffee8a5-d5f4-5090-bc4d-28c30744b17f
DOI: 10.1101/433706

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