Article

A Multi-Modal Deep Learning Framework with Both Sequence and Structure for Tumor Antigens Prediction

2024-11-08

Abstract excerpt

Tumor antigens are key targets in cancer immunotherapies that can be recognized by T cell receptor and induce immune responses. However, precision screening of immunogenic tumor antigens remains a great challenge due to human leukocyte antigen (HLA) restriction and tumor antigen escape. Here, we introduce MultiTAP (Multi-modal Tumor Antigen Predictor), a pioneering multi-modal framework with TCR-peptide-HLA sequen...

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Literature Corpus work: 298d4301-29b9-5f8d-84e5-553ed7361053
DOI: 10.1101/2024.11.06.622193

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