Article

Neural Network Models for Sequence-Based TCR and HLA Association Prediction

2023-05-26

Abstract excerpt

T cells rely on their T cell receptors (TCRs) to recognize foreign antigens presented by human leukocyte antigen (HLA) proteins. TCRs contain a record of an individual’s past immune activities, and some TCRs are observed only in individuals with certain HLA alleles. As a result, characterising TCRs requires a thorough understanding of TCR-HLA associations. To this end, we propose a neural network method named Deep...

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Literature Corpus work: 99f19e44-df28-562f-ac4d-0b2060a7bca6
DOI: 10.1101/2023.05.25.542327

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