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Article

Power of association and linkage tests when the disease alleles are unobserved.

American journal of human genetics - 1 Feb 1999

Tu I P, Whittemore A S

Abstract excerpt

Genomewide association studies have been advocated as a promising alternative to genomewide linkage scans for detection of small-effect genes in complex diseases. Comparisons of power and sample size between the two strategies have shown considerable advantages for the association studies. These...

Topics

Alleles
Gene Frequency
Genetic Linkage
Genetic Markers
Humans
Linkage Disequilibrium
Models, Genetic
Models, Statistical

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9973303
DOI: 10.1086/302253
PMCID: PMC1377775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9973303-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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