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Article

Linkage effects and analysis of finite sample errors in the HapMap.

Human heredity - 1 Jan 2009

Zaitlen Noah, Kang Hyun Min, Eskin Eleazar

Abstract excerpt

The HapMap provides a valuable resource to help uncover genetic variants of important complex phenotypes such as disease risk and outcome. Using the HapMap we can infer the patterns of LD within different human populations. This is a critical step for determining which SNPs to genotype as part of a study, estimating study power, designing a follow-up study to identify the causal variants, 'imputing' untyped SNPs,...

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PMID: 19365134
DOI: 10.1159/000212500
PMCID: PMC2874737

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