Article
Colorectal adenomatous and hyperplastic polyps: smoking and N-acetyltransferase 2 polymorphisms.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 1999
Potter J D, Bigler J, Fosdick L, Bostick R M, Kampman E, Chen C, Louis T A, Grambsch P
Abstract excerpt
Arylamine N-acetyltransferase 2 (NAT2) is involved in both the detoxification and bioactivation of carcinogenic arylamines and other mutagens. This enzyme is polymorphic, and the fast and slow phenotypes are thought to be risk factors for colon and bladder cancer, respectively. Here, we report on...
Topics
- Adenomatous Polyps
- Adult
- Age Factors
- Aged
- Anti-Inflammatory Agents, Non-Steroidal
- Arylamine N-Acetyltransferase
- Carcinogens
- Case-Control Studies
- Colonic Neoplasms
- Colonic Polyps
- Colonoscopy
- Confidence Intervals
- Estrogen Replacement Therapy
- Female