Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acetylation polymorphism and prevalence of colorectal adenomas.

Cancer research - 15 May 1995

Probst-Hensch N M, Haile R W, Ingles S A, Longnecker M P, Han C Y, Lin B K, Lee D B, Sakamoto G T, Frankl H D, Lee E R

Abstract excerpt

Polymorphic N-acetyltransferase (NAT2), an enzyme present in the colon, may effect incidence of colon cancer. Individuals with NAT2 fast acetylator genotypes may have higher colon cancer risks due to faster conversion of certain carcinogens to mutagens. We determined NAT2 genotypes in 447 subjects with distal colon adenomas and in 487 controls. No significant increase in adenoma prevalence among fast acetylators...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Base Sequence
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Molecular Sequence Data

Share to Mutation

Share to Polymorphism, Genetic

Share to Prevalence

Source

Identifiers

PMID: 7743494

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acetylation polymorphism and prevalence of colorectal adenomas.PMID 7743494Read ↗

Colorectal adenomatous and hyperplastic polyps: smoking and N-acetyltransferase 2 polymorphisms.Semantic proximity Read ↗

N-Acetyltransferase 2 genetic polymorphisms and risk of colorectal cancer.Semantic proximity Read ↗

NAT2 fast acetylator genotype is associated with an increased risk of colorectal cancer in Taiwan.Semantic proximity Read ↗

NAT2 fast acetylator genotype and MGMT promoter methylation may contribute to gender difference in K-RAS mutation occurrence in Taiwanese colorectal cancer.Semantic proximity Read ↗

N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.Semantic proximity Read ↗

Absence of association between N-acetyltransferase 2 acetylator status and colorectal cancer susceptibility: based on evidence from 40 studies.Semantic proximity Read ↗

Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma.Semantic proximity Read ↗

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.Semantic proximity Read ↗

Diet, acetylator phenotype, and risk of colorectal neoplasia.Semantic proximity Read ↗

A meta-analysis of the relationship between NAT2 polymorphism and colorectal cancer susceptibility.Semantic proximity Read ↗

N-acetyltransferase 2 (NAT2) gene polymorphisms in colon and lung cancer patients.Semantic proximity Read ↗

N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: a pooled analysis of variations from 59 studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.