Article
N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: a pooled analysis of variations from 59 studies.
PloS one - 1 Jan 2012
Liu Jinxin, Ding Dapeng, Wang Xiaoxue, Chen Yizhi, Li Rong, Zhang Ying, Luo Rongcheng
Abstract excerpt
BACKGROUND: There have been an increasing number of studies with evidence suggesting that the N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NAT2) genotypes may be implicated in the development of colorectal cancer (CRC) and colorectal adenoma (CRA). So far the published data on this association has remained controversial, however. We performed a meta-analysis of case-cohort and case-control studies...
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