Article
Absence of association between N-acetyltransferase 2 acetylator status and colorectal cancer susceptibility: based on evidence from 40 studies.
PloS one - 1 Jan 2012
Zhang Lou qian, Zhou Jian nong, Wang Jun, Liang Guo dong, Li Jing ying, Zhu Yi dan, Su Yun tao
Abstract excerpt
BACKGROUND AND OBJECTIVES: N-Acetyltransferase (NAT) 2 is an important enzyme involved in the metabolism of different xenobiotics, including potential carcinogens, whose phenotypes were reported to be related to individual susceptibility to colorectal cancer (CRC). However, the results remain conflicting. To assess the relationship between NAT2 phenotypes and CRC risk, we performed this meta-analysis. METHODS: A...
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