Article
Prospective study of NAT1 and NAT2 polymorphisms, tobacco smoking and meat consumption and risk of colorectal cancer.
Cancer letters - 8 Aug 2008
Sørensen Mette, Autrup Herman, Olsen Anja, Tjønneland Anne, Overvad Kim, Raaschou-Nielsen Ole
Abstract excerpt
Heterocyclic amines in tobacco smoke and fried meat are activated or detoxified by N-acetyltransferases (NAT1 and NAT2). We identified 379 cases with colorectal cancer (CRC) and 769 sub-cohort members among a cohort of 57,000 members. There were no statistically significant associations between tobacco smoking, consumption of meat (red, processed and fried) and CRC risk. Preference for brown-dark pan-fried meat...
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