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Article

Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2009

Nöthlings Ute, Yamamoto Jennifer F, Wilkens Lynne R, Murphy Suzanne P, Park Song-Yi, Henderson Brian E, Kolonel Laurence N, Le Marchand Loïc

Abstract excerpt

BACKGROUND: N-acetyltransferases (NAT) 1 and 2 are polymorphic enzymes catalyzing the metabolic activation of heterocyclic amines. We investigated the modifying effects of NAT1 and NAT2 polymorphisms on the association of meat consumption, heterocyclic amine intake, and smoking with colorectal cancer risk. METHOD: In the Multiethnic Cohort study, participants completed a smoking history and a food-frequency...

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Identifiers

PMID: 19549810
DOI: 10.1158/1055-9965.EPI-08-1218
PMCID: PMC2771770

Genes

NAT2
NAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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