Article
Effect of chromosome 19 transfer on blood pressure in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999
St Lezin E, Zhang L, Yang Y, Wang J M, Wang N, Qi N, Steadman J S, Liu W, Kren V, Zidek V, Krenova D, Churchill P C, Churchill M C, Pravenec M
Abstract excerpt
Linkage studies in the spontaneously hypertensive rat (SHR) have suggested that a gene or genes regulating blood pressure may exist on rat chromosome 19 in the vicinity of the angiotensinogen gene. To test this hypothesis, we measured blood pressure in SHR progenitor and congenic strains that are genetically identical except for a segment of chromosome 19 containing the angiotensinogen gene transferred from the...
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