Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic isolation of a chromosome 1 region affecting blood pressure in the spontaneously hypertensive rat.

Hypertension (Dallas, Tex. : 1979) - 1 Oct 1997

St Lezin E, Liu W, Wang J M, Wang N, Kren V, Krenova D, Musilova A, Zdobinska M, Zidek V, Lau D, Pravenec M

Abstract excerpt

Recent linkage studies in the spontaneously hypertensive rat (SHR) suggest that a blood pressure regulatory gene or genes may be located on rat chromosome 1q. To investigate this possibility, we replaced a region of chromosome 1 in the SHR (defined by the markers D1Mit3 and Igf2) with the corresp...

Topics

Animals
Blood Pressure
Chromosome Mapping
Chromosomes
Diastole
Genotype
Humans
Male
Rats
Rats, Inbred BN
Rats, Inbred SHR
Species Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Systole

Source

Identifiers

PMID: 9336384
DOI: 10.1161/01.hyp.30.4.854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9336384-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic isolation of a chromosome 1 region affecting blood pressure in the spontaneously hypertensive rat.PMID 9336384Read ↗

Genetic isolation of a chromosome 1 region affecting susceptibility to hypertension-induced renal damage in the spontaneously hypertensive rat.Semantic proximity Read ↗

Isolation of a chromosome 1 region that contributes to high blood pressure and salt sensitivity.Semantic proximity Read ↗

Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat.Semantic proximity Read ↗

Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains.Semantic proximity Read ↗

Isolation of a chromosome 1 region affecting blood pressure and vascular disease traits in the stroke-prone rat model.Semantic proximity Read ↗

Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension.Semantic proximity Read ↗

Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat.Semantic proximity Read ↗

Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat.Semantic proximity Read ↗

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.Semantic proximity Read ↗

Defining a rat blood pressure quantitative trait locus to a <81.8 kb congenic segment: comprehensive sequencing and renal transcriptome analysis.Semantic proximity Read ↗

Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure.Semantic proximity Read ↗

Genetic Dissection of a Blood Pressure Quantitative Trait Locus on Rat Chromosome 1 and Gene Expression Analysis Identifies SPON1 As a Novel Candidate Hypertension GeneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.