Article
Linkage analysis and construction of a congenic strain for a blood pressure QTL on rat chromosome 9.
Genomics - 15 Jul 1998
Rapp J P, Garrett M R, Dene H, Meng H, Hoebee B, Lathrop G M
Abstract excerpt
A blood pressure quantitative trait locus was found (LOD = 5.0) on rat chromosome 9 using a large F2 population (N = 233) derived from Dahl salt-sensitive (S) and Dahl salt-resistant (R) rats. The F2 rats were fed 8% NaCl diet for 8 weeks. A congenic strain introgressing the R low-blood-pressure...
Topics
- Animals
- Animals, Congenic
- Blood Pressure
- Chromosome Mapping
- Diet
- Genotype
- Heart
- Inbreeding
- Inhibins
- Organ Size
- Peptides
- Quantitative Trait, Heritable
- Rats
- Rats, Inbred Dahl
- Sodium Chloride, Dietary