smg-7 is required for mRNA surveillance in Caenorhabditis elegans.

doi:10.1093/genetics/151.2.605

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Article

smg-7 is required for mRNA surveillance in Caenorhabditis elegans.

Genetics - 1 Feb 1999

Cali B M, Kuchma S L, Latham J, Anderson P

Abstract excerpt

Eukaryotic mRNAs that contain premature stop codons are degraded more rapidly than their wild-type counterparts, a phenomenon termed "nonsense-mediated mRNA decay" (NMD) or "mRNA surveillance." Functions of six previously described Caenorhabditis elegans genes, smg-1 through smg-6, are required f...

Topics

Amino Acid Sequence
Animals
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Codon, Terminator
Gene Expression Regulation
Helminth Proteins
Molecular Sequence Data
Mutation
Protein Biosynthesis
RNA, Messenger
Sequence Alignment

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