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Article

mRNA surveillance mitigates genetic dominance in Caenorhabditis elegans.

Molecular & general genetics : MGG - 1 Nov 1998

Cali B M, Anderson P

Abstract excerpt

Nonsense mutant mRNAs are unstable in all eucaryotes tested, a phenomenon termed nonsense-mediated mRNA decay (NMD) or mRNA surveillance. Functions of the seven smg genes are required for mRNA surveillance in Caenorhabditis elegans. In Smg(+) genetic backgrounds, nonsense-mutant mRNAs are unstable, while in Smg(-) backgrounds such mRNAs are stable. Previous work has demonstrated that the elevated level of...

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PMID: 9862469
DOI: 10.1007/s004380050883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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