Article

Release of human TFIIB from actively transcribing complexes is triggered upon synthesis of 7 nt and 9 nt RNAs

2019-12-20

Abstract excerpt

RNA polymerase II (Pol II) and its general transcription factors assemble on the promoters of mRNA genes to form large macromolecular complexes that initiate transcription in a regulated manner. During early transcription these complexes undergo dynamic rearrangement and disassembly as Pol II moves away from the start site of transcription and transitions into elongation. One step in disassembly is the release of...

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Literature Corpus work: efd63c29-9e82-57e8-b057-30aef461d458
DOI: 10.1101/2019.12.19.882902

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