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Article

The role of TFIIB-RNA polymerase II interaction in start site selection in yeast cells.

Nucleic acids research - 15 Jul 2002

Zhang Dong-Yi, Carson Daniel J, Ma Jun

Abstract excerpt

Previous studies have established a critical role of both TFIIB and RNA polymerase II (RNAPII) in start site selection in the yeast Saccharomyces cerevisiae. However, it remains unclear how the TFIIB-RNAPII interaction impacts on this process since such an interaction can potentially influence both preinitiation complex (PIC) stability and conformation. In this study, we further investigate the role of TFIIB in...

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Identifiers

PMID: 12136090
DOI: 10.1093/nar/gkf422
PMCID: PMC135743

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The role of TFIIB-RNA polymerase II interaction in start site selection in yeast cells.PMID 12136090Read ↗

Functional interaction between TFIIB and the Rpb2 subunit of RNA polymerase II: implications for the mechanism of transcription initiation.Semantic proximity Read ↗

Important role in transcription start site selection for the RNA polymerase II-TFIIE-TFIIH interface in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genetic dissection of transcription start site selection by RNA polymerase II in Saccharomyces cerevisiae.Semantic proximity Read ↗

A functional role for the switch 2 region of yeast RNA polymerase II in transcription start site utilization and abortive initiation.Semantic proximity Read ↗

Assembly of transcription factor IIB at a promoter in vivo requires contact with RNA polymerase II.Semantic proximity Read ↗

Mechanism of start site selection by RNA polymerase II: interplay between TFIIB and Ssl2/XPB helicase subunit of TFIIH.Semantic proximity Read ↗

Evidence that transcription factor IIB is required for a post-assembly step in transcription initiation.Semantic proximity Read ↗

Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex.Semantic proximity Read ↗

The Saccharomyces cerevisiae RNA polymerase III recruitment factor subunits Brf1 and Bdp1 impose a strict sequence preference for the downstream half of the TATA box.Semantic proximity Read ↗

Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB.Semantic proximity Read ↗

Mutational analysis of yeast TFIIB. A functional relationship between Ssu72 and Sub1/Tsp1 defined by allele-specific interactions with TFIIB.Semantic proximity Read ↗

Core promoter-dependent TFIIB conformation and a role for TFIIB conformation in transcription start site selection.Semantic proximity Read ↗

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