Article
An activator binding module of yeast RNA polymerase II holoenzyme.
Molecular and cellular biology - 1 Apr 1999
Lee Y C, Park J M, Min S, Han S J, Kim Y J
Abstract excerpt
The Mediator complex of Saccharomyces cerevisiae is required for both general and regulated transcription of RNA polymerase II (PolII) and is composed of two stable subcomplexes (Srb4 and Rgr1 subcomplexes). To decipher the function of each Mediator subcomplex and to delineate the functional relationship between the subcomplexes, we characterized the compositions and biochemical activities of PolII-Mediator...
Topics
- DNA-Binding Proteins
- Fungal Proteins
- Holoenzymes
- Mediator Complex
- Mutation
- Peptide Fragments
- Phosphorylation
- Protein Binding
- RNA Polymerase II
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- TATA-Binding Protein Associated Factors
- TATA-Box Binding Protein