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Article

Glucocorticoid replacement, but not corticotropin-releasing hormone deficiency, prevents adrenalectomy-induced anorexia in mice.

Endocrinology - 1 Jan 1999

Jacobson L

Abstract excerpt

There is considerable evidence that CRH can suppress food intake. As hypothalamic CRH, a main site of CRH expression, is also negatively regulated by glucocorticoids, it is unclear whether anorexia and weight loss in adrenal insufficiency are attributable to elevated CRH or to decreased glucocort...

Topics

Adrenalectomy
Animals
Anorexia
Body Weight
Corticosterone
Corticotropin-Releasing Hormone
Energy Intake
Genotype
Glucocorticoids
Insulin
Leptin
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Mice, Knockout

Proteins

Source

Identifiers

PMID: 9886840
DOI: 10.1210/endo.140.1.6416

Genes

CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9886840-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Glucocorticoid replacement, but not corticotropin-releasing hormone deficiency, prevents adrenalectomy-induced anorexia in mice.PMID 9886840Read ↗

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