Article
Normal suppression of the reproductive axis following stress in corticotropin-releasing hormone-deficient mice.
Endocrinology - 1 Apr 1999
Jeong K H, Jacobson L, Widmaier E P, Majzoub J A
Abstract excerpt
The hypothalamic neuropeptide CRH has been postulated to inhibit LH secretion by a central action within the brain. To characterize the physiological significance of CRH in stressor-induced inhibition of LH secretion, CRH-deficient and wild-type mice were subjected to restraint or food withdrawal, and plasma LH levels were determined. The proestrus LH surge of female mice was equally suppressed by restraint in...
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