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Article

Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress.

Peptides - 1 May 2001

Coste S C, Murray S E, Stenzel-Poore M P

Abstract excerpt

This review highlights new information gained from studies using recently developed animal models that harbor specific alterations in corticotropin-releasing hormone (CRH) pathways. We discuss features of a transgenic mouse model of chronic CRH overexpression and two mouse models that lack either CRH receptor type 1 (CRH-R1) or type 2 (CRH-R2). Together these models provide new insights into the role of CRH...

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Source

Identifiers

PMID: 11337086
DOI: 10.1016/s0196-9781(01)00386-2

Genes

CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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