Article
Function of the hypothalamo-hypophyseal-adrenal system in mice with ectopic hyperproduction of the agouti protein.
Neuroscience and behavioral physiology - 1 Feb 2005
Karkaeva N R, Bazhan N M, Yakovleva T V, Makarova E N
Abstract excerpt
The agouti protein is known to compete with the melanocortin hormones (ACTH, melanocyte-stimulating hormone) at melanocortin receptors, which in turn are involved in controlling the central and peripheral components of the hypothalamo-hypophyseal-adrenal system. The aim of the present work was therefore to assess the effects of the dominant mutation Agouti yellow (A(y)/a), which induces ectopic hyperproduction of...
Topics
- Adrenal Glands
- Adrenocorticotropic Hormone
- Agouti Signaling Protein
- Animals
- Corticosterone
- Dexamethasone
- Genotype
- Glucocorticoids
- Hypothalamo-Hypophyseal System
- In Vitro Techniques
- Intercellular Signaling Peptides and Proteins
