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Article

Adrenalectomy and castration in the genetically obese (ob/ob) mouse.

Obesity research - 1 Sept 1993

Shimizu H, Ohshima K, Bray G A, Peterson M, Swerdloff R S

Abstract excerpt

The present studies have tested the hypothesis that adrenalectomy could modify the phenotypic expression of genetic obesity by examining the effects of adrenalectomy on the function of the gonadal system in lean and ob/ob mice. Corticosterone concentrations were undetectable in the adrenalectomized animals. Adrenalectomy significantly slowed the weight gain of obese mice in comparison to sham-adrenalectomized...

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Source

Identifiers

PMID: 16353363
DOI: 10.1002/j.1550-8528.1993.tb00016.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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