Article
CRH-deficient mice have a normal anorectic response to chronic stress.
Regulatory peptides - 22 Oct 1999
Weninger S C, Muglia L J, Jacobson L, Majzoub J A
Abstract excerpt
Many studies have implicated corticotropin-releasing hormone (CRH) as a mediator of stress-induced decreases in food intake. However, urocortin, sauvagine, and urotensin, other members of the family of CRH-like molecules, have also been shown to be potent inhibitors of food intake. This raises the possibility that a CRH-related molecule might also be responsible for stress-induced anorexia. We therefore examined...
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