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Article

Agouti yellow mutation increases adrenal response to ACTH in mice.

European journal of endocrinology - 1 Aug 2004

Bazhan Nadezhda M, Shevchenko Antonina Y, Karkaeva Nelli R, Yakovleva Tatyana V, Makarova Elena N

Abstract excerpt

OBJECTIVE: Agouti protein (AP) and agouti-related protein with a similar sequence and action are endogenous antagonists of melanocortin receptors, implicated in the control of the hypothalamo-pituitary-adrenal (HPA) axis. Dominant mutation of the agouti gene (agouti yellow (A(y))) in heterozygous A(y)/a mice leads to ectopic overexpression of AP and produces an obese phenotype. The existing data on the HPA...

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Source

Identifiers

PMID: 15296483
DOI: 10.1530/eje.0.1510265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Agouti yellow mutation increases adrenal response to ACTH in mice.PMID 15296483Read ↗

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