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Article

Mechanism of suppression of hepatitis B virus precore RNA transcription by a frequent double mutation.

Journal of virology - 1 Feb 1999

Li J, Buckwold V E, Hon M W, Ou J H

Abstract excerpt

A double mutation which converts nucleotide 1765 from A to T and nucleotide 1767 from G to A is frequently found in the hepatitis B virus (HBV) genome isolated from HBV patients with chronic hepatitis symptoms. This double mutation is located in the core promoter that controls the transcription of the precore RNA and the core RNA. In addition, this double mutation also resides in the X protein coding sequence,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9882327
DOI: 10.1128/JVI.73.2.1239-1244.1999
PMCID: PMC103946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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