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Article

Regulation of hepatitis B virus core promoter by transcription factors HNF1 and HNF4 and the viral X protein.

Journal of virology - 1 Jul 2004

Zheng Yanyan, Li Jie, Ou Jing-hsiung

Abstract excerpt

Hepatitis B virus (HBV) core promoter contains a binding site for nuclear receptors. A natural double mutation in this binding site, which changes nucleotide (nt) 1765 from A to T and nt 1767 from G to A, selectively abolishes the binding of several nuclear receptors without affecting that of HNF4. This double mutation also creates a binding site for the transcription factor HNF1 and changes two amino acids in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatocyte Nuclear Factor 1

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Source

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Identifiers

PMID: 15194767
DOI: 10.1128/JVI.78.13.6908-6914.2004
PMCID: PMC421633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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