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Article

Prevalence of mutations in core promoter/precore region in Japanese patients with chronic hepatitis B virus infection.

Digestive diseases and sciences - 1 Nov 1998

Nagasaka A, Hige S, Marutani M, Tsunematsu I, Saito M, Yamamoto Y, Konishi S, Asaka M

Abstract excerpt

We examined the frequency and significance of mutations in the core promoter and precore region in 103 Japanese patients with chronic hepatitis B virus (HBV) infection. HBV DNAs from the patients' sera were amplified by polymerase chain reaction and were directly sequenced. A double mutation (T1762 A1764) in the core promoter was frequently observed in the patients regardless of HBeAg status except for...

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PMID: 9824137
DOI: 10.1023/a:1026690400897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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