Article
Development of congenics for hypnotic sensitivity to ethanol by QTL-marker-assisted counter selection.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998
Bennett B, Johnson T E
Abstract excerpt
Mouse strains congenic for individual quantitative trait loci (QTLs) conferring hypnotic sensitivity to ethanol were constructed by backcrossing genotypically selected ILS x ISS N2 individuals to either inbred Long Sleep (ILS) or inbred Short Sleep (ISS) mice. We used a novel "speed congenic" app...
Topics
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Ethanol
- Female
- Genetic Markers
- Genotype
- Hypnotics and Sedatives
- Male
- Mice
- Mice, Congenic
- Mice, Inbred Strains
- Phenotype
- Quantitative Trait, Heritable
- Sex Factors
- Sleep
- Specific Pathogen-Free Organisms
