Article
Genetic dissection of quantitative trait locus for ethanol sensitivity in long- and short-sleep mice.
Genes, brain, and behavior - 1 Aug 2008
Bennett B, Carosone-Link P, Beeson M, Gordon L, Phares-Zook N, Johnson T E
Abstract excerpt
Interval-specific congenic strains (ISCS) allow fine mapping of a quantitative trait locus (QTL), narrowing its confidence interval by an order of magnitude or more. In earlier work, we mapped four QTL specifying differential ethanol sensitivity, assessed by loss of righting reflex because of ethanol (LORE), in the inbred long-sleep (ILS) and inbred short-sleep (ISS) strains, accounting for approximately 50% of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
