Congenic strains developed for alcohol- and drug-related phenotypes.

doi:10.1016/s0091-3057(00)00412-3

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Article

Congenic strains developed for alcohol- and drug-related phenotypes.

Pharmacology, biochemistry, and behavior - 1 Dec 2000

Bennett B

Abstract excerpt

Quantitative trait loci (QTLs) for many alcohol- and drug-related traits have been mapped using well-accepted mapping techniques. The ultimate goal of gene identification necessitates confirmation of the QTL and reduction of the interval surrounding the QTL; both can be accomplished in congenic strains. These strains carry a chromosomal region introgressed from a donor strain onto the genetic background of a...

Topics

Alcoholism
Animals
Chromosome Mapping
Chromosomes
Inbreeding
Mice
Mice, Congenic
Mice, Inbred BALB C
Mice, Inbred C57BL
Motor Activity
Phenotype
Quantitative Trait, Heritable
Substance Withdrawal Syndrome
Substance-Related Disorders

Source

Open in PubMed

Identifiers

PMID: 11166057
DOI: 10.1016/s0091-3057(00)00412-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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